ʻO Cushing's Syndrome (Fragile Skin Syndrome) i nā ʻīlio

He ʻōnaehana kū hoʻokahi ke kino o ka ʻīlio me ka nui o nā kaʻina biochemical. ʻO ke kiʻekiʻe o ka ulu kino a me ka noʻonoʻo o ka holoholona e pili ana i ko lākou maikaʻi. Hoʻopili ʻia ka ʻaoʻao hormonal e ka hana kūpono o nā mea huna o loko. A inā loaʻa kahi pilikia endocrine, hiki i ka ʻīlio ke loaʻa i ka Cushing's Syndrome.

Nā kumu o ka maʻi

ʻO Cushing's Syndrome i nā ʻīlio kekahi o nā maʻi hormonal maʻamau. Me ia, aia ka hoʻonui nui ʻana o nā glucocorticoids i hana ʻia e nā kelepa adrenal. ʻO ka pinepine, loaʻa nā ʻīlio ʻoi aku ma mua o 7 mau makahiki i ka maʻi maʻi, akā hiki ke hoʻopilikia ʻia nā ʻīlio ʻōpio. ʻO nā kumu nui o ka maʻi:

1. Nā ʻōpū o ka pituitary gland. Ho'ōki ia i ka hana ʻana i ka hormone ACTH i ka nui kūpono a ʻaʻole hiki ke kāohi i ke kiʻekiʻe o ka cortisol i loko o ke koko. Loaʻa kēia ʻano o ka maʻi ʻili palupalu i 85-90% o nā ʻīlio. 

2. ʻO nā puʻupuʻu o ka adrenal glands. I kēia hihia, hana ʻia ka nui o ka cortisol ke komo ka ʻīlio i nā kūlana koʻikoʻi a makaʻu loa. ʻO ka nui a i ʻole ka nele o ka cortisol kahi ala pololei i ka hoʻomohala ʻana i nā pathologies koʻikoʻi i loko o ke kino o ka holoholona. ʻOi aku ka maʻamau o ka pathology o ka adrenal glands i nā ʻīlio kahiko ma 11-12 mau makahiki. 

3. Hoʻololi lua (iatrogenic hyperadrenocorticism). Loaʻa ia ma muli o ka mālama lōʻihi o nā allergies, dermatitis a me ka ʻeha nui me ka nui o nā lāʻau hormonal mai ka hui glucocorticoid.

Pehea e ʻike ai a mālama ai i ka Cushing's Syndrome

Hoʻomaka ka maʻi me nā hōʻailona i ʻōlelo ʻia:

• ka mimi pinepine, kahi hiki ole i ka ilio ke hoomanawanui a mimi ma ka home;
• makewai ikaika a kinai ole;
• nawaliwali, lethargy, apathy, hiamoe;
• hoʻonui i ka ʻai me ka ʻai ʻana i nā mea hiki ʻole ke ʻai ʻia;
• ʻo ka ʻōpū o ka ʻōpū ma muli o ke atrophy o ka ʻiʻo;
• lauoho lauoho ma ka opu a me na aoao;
• ka poho kaumaha a i ʻole ke kaumaha me ka meaʻai maʻamau;
• nele i ka hoʻohui ʻana;
• nā pilikia hormonal: hoʻopau i ka estrus i nā wahine a me ka atrophy o nā testicles i nā kāne;
• hoʻololi i ka ʻano: lilo ka ʻīlio aloha i ka makaʻu, huhū.

He mea hoʻopunipuni kēia maʻi, no ka mea, ua hui pū ʻia me nā pilikia like ʻole: arterial hypertension, nā maʻi o nā puʻupaʻa a me nā ʻāpana urinary, diabetes mellitus, osteoporosis, nā maʻi i loko o nā ʻōpū hānau. 

ʻO nā ʻano e like me ke kahu hipa, dachshund, beagle, terrier, poodle, labrador, boxer e predisposed i ka maʻi Cushing, no laila pono e hoʻāʻo ʻia nā mea nona kēia manawa no ka ʻike ʻana i kēia pathology. ʻO ka pinepine, loaʻa ka maʻi i nā ʻīlio o nā ʻano nui i ʻoi aku ma mua o 20 kg. Hana ʻia ka hōʻoia e ka mea lapaʻau a hiki ke komo i ka hoʻokolohua kino, nā hoʻāʻo koko a me nā biochemical, urinalysis, X-rays, MRI o ka pituitary a me adrenal glands, ultrasound, a me nā hoʻokolohua e hoʻoholo ai i ke kiʻekiʻe o ka cortisol i loko o ke koko. No ka mālama ʻana, hoʻohana ka veterinarian i nā ʻano lāʻau lapaʻau a me nā ʻano hana:

1. I ka hihia mua, hiki i ke kauka ke kauoha i ka lāʻau lapaʻau e hoʻomalu i nā pae cortisol. 

2. I ka lua o ka hihia, hiki iā ia ke wehe i hoʻokahi a i ʻole ʻelua o ka adrenal gland a kau i ka ʻīlio i ka hormone therapy.

I nā hihia koʻikoʻi, hiki i ke kauka lapaʻau ke kuhikuhi i ka lāʻau lapaʻau ola. ʻO kahi hōʻailona o ka hoʻihoʻi ʻana o ka holoholona ʻo ka emi ʻana o ka ʻai a me ka inu wai maʻamau. Inā ʻaʻole hoʻomaka ka mālama ʻana i ka manawa, make paha ka ʻīlio i ka luhi. 

Hiki i ke kanaka ke loaʻa i ka maʻi Cushing?

ʻAʻole hiki i ka maʻi Cushing ke loaʻa i nā ʻīlio a me nā pōpoki wale nō, akā i nā kānaka pū kekahi, akā ʻaʻole ia he maʻi lele. ʻO nā hōʻike lapaʻau o ka maʻi maʻi i nā ʻīlio a me nā kānaka he ʻano like loa: i loko o ke kanaka, ʻike ʻia ka momona o ka ʻōpū, ʻike ʻia nā loli o ka ʻili a me ka atrophy muscle. Inā hoʻomaka ka maʻi, hiki i ke kanaka ke nalowale i ka nui o ka ʻiʻo a me ka iwi, hoʻomohala i ka hypertension, type 2 diabetes, a loaʻa i nā maʻi maʻamau. No nā kamaliʻi a me nā ʻōpio, he maʻi maʻamau kēia.

Pehea ka ʻokoʻa o ka maʻi Cushing i nā pōpoki a me nā ʻīlio?

ʻAʻole like me nā ʻīlio, ʻaʻole loaʻa ka Cushing's Syndrome i nā pōpoki. 

• ʻO kekahi o nā ʻokoʻa i ka hōʻike lapaʻau o ka maʻi ʻaʻole maikaʻi ka mālama ʻia ʻana o ka maʻi diabetes mellitus me ka ikaika o ka insulin. Lilo ka ʻili a palupalu, lilo koke ke kaumaha o ka pōpoki. 

• ʻO ka lua o ka ʻokoʻa, ʻo ia ka lauoho ulu ʻole ma hope o ka ʻako ʻana, ka ʻōhule i ka huelo a maloʻo. 

• ʻO ke kolu o ka ʻokoʻa i ka maʻi, ʻo ia ka hoʻokumu ʻana o ka calcifications ʻili i nā ʻīlio ma ka ʻāʻī a me nā pepeiao, ʻaʻole i loaʻa i nā pōpoki.

Pehea e pale ai i ka mai

ʻO ke ʻano iatrogenic wale nō o ka maʻi ʻo Cushing i nā ʻīlio hiki ke pale ʻia e kahi ʻano haʻahaʻa o nā lāʻau hormonal i ka mālama ʻana. ʻAʻole pono ʻoe e kuhikuhi iā ʻoe iho i kēlā ʻano lapaʻau - pono ʻoe e hele i nā hoʻāʻo āpau a kamaʻilio pū me kahi kauka holoholona. I kēlā me kēia hihia, pono e nānā nā mea nona ke ʻano o ka ʻaʻahu o ka ʻīlio, hoʻololi i ka ʻai, hoʻonui i ka make wai a me ka nalowale o ka lauoho, a inā ʻike ʻia kekahi mau hōʻailona, ​​​​e hoʻopili i kahi keʻena lapaʻau holoholona. E kōkua kēia mau hōʻailona āpau i ka ʻike ʻana i ka maʻi i ka manawa a mālama i ke olakino a ola ka holoholona no kekahi mau makahiki.